Nomogram predicts survival benefit from preoperative radiotherapy for non-metastatic breast cancer: A SEER-based study.

ABSTRACT:

Background

To estimate survival in non-metastatic breast cancer patients who failed to achieve a pathological complete response (pCR) more effectively, we combined the clinicpathological characteristics after preoperative radiation therapy (pRT) and established a novel nomogram.

Materials and methods

Using the Surveillance, Epidemiology, and End Results (SEER) database, we identified 2,545 non-metastatic breast cancer patients who underwent pRT between 1998 and 2013. Based on the registries of patients, the primary cohort divided into training set (n = 1,692) and validation set (n = 853). Nomograms were established by training set and validated by validation set.

Results

According to the multivariate analysis of training set, nomogram which combined age at diagnosed,

SUBMITTER: Liu J 

PROVIDER: S-EPMC5564813 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature