Multiple PPR protein interactions are involved in the RNA editing system in Arabidopsis mitochondria and plastids.

ABSTRACT: Recent identification of several different types of RNA editing factors in plant organelles suggests complex RNA editosomes within which each factor has a different task. However, the precise protein interactions between the different editing factors are still poorly understood. In this paper, we show that the E⁺-type pentatricopeptide repeat (PPR) protein SLO2, which lacks a C-terminal cytidine deaminase-like DYW domain, interacts in vivo with the DYW-type PPR protein DYW2 and the P-type PPR protein NUWA in mitochondria, and that the latter enhances the interaction of the former ones. These results may reflect a protein scaffold or complex stabilization role of NUWA between E⁺-type PPR and DYW2 proteins. Interestingly, DYW2 and NUWA also interact in chloroplasts, and

SUBMITTER: Andres-Colas N 

PROVIDER: S-EPMC5565447 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature