Network analysis identifies common genes associated with obesity in six obesity-related diseases.

ABSTRACT: Obesity has been reported to be associated with many diseases. However, common obesity-induced biological processes have not been evaluated across these diseases. We identified genes associated with obesity and obesity-related diseases, and used them to construct protein‒protein interaction networks. We also analyzed gene ontology (GO) in those genes overlapping between obesity and disease. Our work identifies gene modules common to obesity and obesity-related diseases, which can provide a basis for understanding the process of how obesity induces disease.

SUBMITTER: Su LN 

PROVIDER: S-EPMC5565522 | biostudies-literature | 2017 Aug.

REPOSITORIES: biostudies-literature