Evaluation of hyperacute infarct volume using ASPECTS and brain CT perfusion core volume.

ABSTRACT:

Objective

To compare the accuracy of Alberta Stroke Program Early Computed Tomography Score (ASPECTS) and CT perfusion to detect established infarction in acute anterior circulation stroke.

Methods

We performed an observational study in 59 acute anterior circulation ischemic stroke patients who underwent brain noncontrast CT, CT perfusion, and MRI within 100 minutes from CT imaging. ASPECTS scores were calculated by 4 blinded vascular neurologists. The accuracy of ASPECTS and CT perfusion core volume to detect an acute MRI diffusion lesion of ≥70 mL was evaluated using receiver operating characteristics analysis and optimum cutoff values were calculated using Youden J.

Results

Median ASPECTS score was 8 (interquartile range [IQR] 5-9). Median CT perfusion core volume

SUBMITTER: Demeestere J 

PROVIDER: S-EPMC5567320 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature