Assembly of a functional and responsive microstructure by heat bonding of DNA-grafted colloidal brick.

ABSTRACT: A micromachine constructed to possess various chemical and mechanical functions is one of the ultimate targets of technology. Conventional lithographic processes can be used to form complicated structures. However, they are basically limited to rigid and static structures with poor surface properties. Here, we demonstrate a novel method for assembling responsive and functional microstructures from diverse particles modified with DNA strands. The DNA strands are designed to form hairpins at room temperature and denature when heated. Structures are assembled through the simultaneous manipulation and heating of particles with "hot" optical tweezers, which incorporates the particles one by one. The flexible connection formed by DNA strands allows the responsive deformation of the structures wi

SUBMITTER: Sakamoto Y 

PROVIDER: S-EPMC5567359 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature