Unitas: the universal tool for annotation of small RNAs.

ABSTRACT:

Background

Next generation sequencing is a key technique in small RNA biology research that has led to the discovery of functionally different classes of small non-coding RNAs in the past years. However, reliable annotation of the extensive amounts of small non-coding RNA data produced by high-throughput sequencing is time-consuming and requires robust bioinformatics expertise. Moreover, existing tools have a number of shortcomings including a lack of sensitivity under certain conditions, limited number of supported species or detectable sub-classes of small RNAs.

Results

Here we introduce unitas, an out-of-the-box ready software for complete annotation of small RNA sequence datasets, supporting the wide range of species for which non-coding RNA reference sequences are avail

SUBMITTER: Gebert D 

PROVIDER: S-EPMC5567656 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature