Early life bisphenol A exposure and neurobehavior at 8years of age: Identifying windows of heightened vulnerability.

ABSTRACT:

Background

Early life BPA exposure could affect neurobehavior, but few studies have investigated whether there are developmental periods when the fetus or child is more vulnerable to these potential effects.

Objectives

We explored windows of vulnerability to BPA exposure in a multiethnic cohort of 228 mothers and their children from Cincinnati, Ohio.

Methods

We measured urinary BPA concentrations at up to two prenatal and six postnatal time points from the 2nd trimester of pregnancy until the child was age 8years. At age 8years, we administered the Behavioral Assessment System for Children-2 (BASC-2), Behavior Rating Inventory of Executive Function, and Wechsler Intelligence Scale for Children-IV. We estimated covariate-adjusted differences in composite scores from ea

SUBMITTER: Stacy SL 

PROVIDER: S-EPMC5567845 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature