Multi-site exploration of sex differences in brain reactivity to smoking cues: Consensus across sites and methodologies.

ABSTRACT:

Background

Biological sex influences cigarette smoking behavior. More men than women smoke, but women have a harder time quitting. Sex differences in smoking cue (SC) reactivity may underlie such behavioral differences. However, the influence of sex on brain reactivity to SCs has yielded inconsistent findings suggesting the need for continued study. Here, we investigated the effect of sex on SC reactivity across two sites using different imaging modalities and SC stimulus types.

Methods

Pseudo-continuous arterial spin-labeled (pCASL) perfusion functional magnetic resonance imaging (fMRI) was used to assess brain responses to SC versus non-SC videos in 40 smokers (23 females) at the University of Pennsylvania. BOLD fMRI was used to assess brain responses to SC versus non-SC s

SUBMITTER: Dumais KM 

PROVIDER: S-EPMC5567981 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature