Task-Related Modulations of BOLD Low-Frequency Fluctuations within the Default Mode Network.

ABSTRACT: Spontaneous low-frequency Blood-Oxygenation Level-Dependent (BOLD) signals acquired during resting state are characterized by spatial patterns of synchronous fluctuations, ultimately leading to the identification of robust brain networks. The resting-state brain networks, including the Default Mode Network (DMN), are demonstrated to persist during sustained task execution, but the exact features of task-related changes of network properties are still not well characterized. In this work we sought to examine in a group of 20 healthy volunteers (age 33 ± 6 years, 8 F/12 M) the relationship between changes of spectral and spatiotemporal features of one prominent resting-state network, namely the DMN, during the continuous execution of a working memory n-back task. We found that task execution

SUBMITTER: Tommasin S 

PROVIDER: S-EPMC5568127 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature