Ontology highlight
ABSTRACT:
SUBMITTER: Probst S
PROVIDER: S-EPMC5568967 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Genesis (New York, N.Y. : 2000) 20170714 8
The T-box transcription factor Eomes (also known as Tbr2) shows short-lived expression in various localized domains of the embryo, including epiblast cells during gastrulation and intermediate progenitor cells in the cerebral cortex. In these tissues Eomes fulfills crucial roles for lineage specification of progenitors. To directly observe Eomes-dependent cell lineages in the living embryo, we generated a novel dual-fluorescence reporter allele that expresses a membrane-bound tdTomato protein fo ...[more]