GalaxyHomomer: a web server for protein homo-oligomer structure prediction from a monomer sequence or structure.

ABSTRACT: Homo-oligomerization of proteins is abundant in nature, and is often intimately related with the physiological functions of proteins, such as in metabolism, signal transduction or immunity. Information on the homo-oligomer structure is therefore important to obtain a molecular-level understanding of protein functions and their regulation. Currently available web servers predict protein homo-oligomer structures either by template-based modeling using homo-oligomer templates selected from the protein structure database or by ab initio docking of monomer structures resolved by experiment or predicted by computation. The GalaxyHomomer server, freely accessible at http://galaxy.seoklab.org/homomer, carries out template-based modeling, ab initio docking or both depending on the availability of p

SUBMITTER: Baek M 

PROVIDER: S-EPMC5570155 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature