PlantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters.

ABSTRACT: Plant specialized metabolites are chemically highly diverse, play key roles in host-microbe interactions, have important nutritional value in crops and are frequently applied as medicines. It has recently become clear that plant biosynthetic pathway-encoding genes are sometimes densely clustered in specific genomic loci: biosynthetic gene clusters (BGCs). Here, we introduce plantiSMASH, a versatile online analysis platform that automates the identification of candidate plant BGCs. Moreover, it allows integration of transcriptomic data to prioritize candidate BGCs based on the coexpression patterns of predicted biosynthetic enzyme-coding genes, and facilitates comparative genomic analysis to study the evolutionary conservation of each cluster. Applied on 48 high-quality plant genomes, plant

SUBMITTER: Kautsar SA 

PROVIDER: S-EPMC5570173 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature