ConTra v3: a tool to identify transcription factor binding sites across species, update 2017.

ABSTRACT: Transcription factors are important gene regulators with distinctive roles in development, cell signaling and cell cycling, and they have been associated with many diseases. The ConTra v3 web server allows easy visualization and exploration of predicted transcription factor binding sites (TFBSs) in any genomic region surrounding coding or non-coding genes. In this updated version, with a completely re-implemented user interface using latest web technologies, users can choose from nine reference organisms ranging from human to yeast. ConTra v3 can analyze promoter regions, 5΄-UTRs, 3΄-UTRs and introns or any other genomic region of interest. Thousands of position weight matrices are available to choose from for detecting specific binding sites. Besides this visualization option, additional

SUBMITTER: Kreft L 

PROVIDER: S-EPMC5570180 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature