The impact of body mass index and height on the risk for glioblastoma and other glioma subgroups: a large prospective cohort study.

ABSTRACT:

Background

Glioma comprises a heterogeneous group of mostly malignant brain tumors, whereof glioblastoma (GBM) represents the largest and most lethal subgroup. Body height and body mass index (BMI) are risk factors for other cancers, but no previous study has examined anthropometric data in relation to different glioma subgroups.

Methods

This prospective cohort study includes 1.8 million Norwegian women and men between ages 14 and 80 years at baseline. Body weight and height were measured, and incident cases of glioma were identified by linkage to the National Cancer Registry. Cox regression analyses were performed to evaluate risk for different glioma subgroups in relation to anthropometric measures.

Results

During 54 million person-years of follow-up, 4,382 gliomas

SUBMITTER: Wiedmann MKH 

PROVIDER: S-EPMC5570185 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature