WoPPER: Web server for Position Related data analysis of gene Expression in Prokaryotes.

ABSTRACT: The structural and conformational organization of chromosomes is crucial for gene expression regulation in eukaryotes and prokaryotes as well. Up to date, gene expression data generated using either microarray or RNA-sequencing are available for many bacterial genomes. However, differential gene expression is usually investigated with methods considering each gene independently, thus not taking into account the physical localization of genes along a bacterial chromosome. Here, we present WoPPER, a web tool integrating gene expression and genomic annotations to identify differentially expressed chromosomal regions in bacteria. RNA-sequencing or microarray-based gene expression data are provided as input, along with gene annotations. The user can select genomic annotations from an internal d

SUBMITTER: Puccio S 

PROVIDER: S-EPMC5570229 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature