DNAproDB: an interactive tool for structural analysis of DNA-protein complexes.

ABSTRACT: Many biological processes are mediated by complex interactions between DNA and proteins. Transcription factors, various polymerases, nucleases and histones recognize and bind DNA with different levels of binding specificity. To understand the physical mechanisms that allow proteins to recognize DNA and achieve their biological functions, it is important to analyze structures of DNA-protein complexes in detail. DNAproDB is a web-based interactive tool designed to help researchers study these complexes. DNAproDB provides an automated structure-processing pipeline that extracts structural features from DNA-protein complexes. The extracted features are organized in structured data files, which are easily parsed with any programming language or viewed in a browser. We processed a large number o

SUBMITTER: Sagendorf JM 

PROVIDER: S-EPMC5570235 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature