ModFOLD6: an accurate web server for the global and local quality estimation of 3D protein models.

ABSTRACT: Methods that reliably estimate the likely similarity between the predicted and native structures of proteins have become essential for driving the acceptance and adoption of three-dimensional protein models by life scientists. ModFOLD6 is the latest version of our leading resource for Estimates of Model Accuracy (EMA), which uses a pioneering hybrid quasi-single model approach. The ModFOLD6 server integrates scores from three pure-single model methods and three quasi-single model methods using a neural network to estimate local quality scores. Additionally, the server provides three options for producing global score estimates, depending on the requirements of the user: (i) ModFOLD6_rank, which is optimized for ranking/selection, (ii) ModFOLD6_cor, which is optimized for correlations of pr

SUBMITTER: Maghrabi AHA 

PROVIDER: S-EPMC5570241 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature