Shared features of cryptic plasmids from environmental and pathogenic Francisella species.

ABSTRACT: The Francisella genus includes several recognized species, additional potential species, and other representatives that inhabit a range of incredibly diverse ecological niches, but are not closely related to the named species. Francisella species have been obtained from a wide variety of clinical and environmental sources; documented species include highly virulent human and animal pathogens, fish pathogens, opportunistic human pathogens, tick endosymbionts, and free-living isolates inhabiting brackish water. While more than 120 Francisella genomes have been sequenced to date, only a few contain plasmids, and most of these appear to be cryptic, with unknown benefit to the host cell. We have identified several putative cryptic plasmids in the sequenced genomes of three Francisella novicida

SUBMITTER: Challacombe JF 

PROVIDER: S-EPMC5570271 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature