Noninvasive experimental bladder pain assessment in painful bladder syndrome.

ABSTRACT:

Objective

To compare bladder sensitivity between patients with pelvic pain and patients who were pain free, undergoing noninvasive, controlled bladder distension via diuresis. We also sought to measure potential mechanisms underlying bladder sensitivity.

Design

Prospective observational study.

Setting

Community teaching hospital.

Population

Reproductive-age women with non-bladder chronic pelvic pain (CPP, n = 23), painful bladder syndrome (PBS, n = 23), and pelvic pain-free controls (n = 42) METHODS: Participants were compared on cystometric capacity, pelvic floor pressure-pain thresholds (PPTs), pelvic muscle function, O'Leary-Sant bladder questionnaire, and psychosocial instruments using Wilcoxon rank-sum tests. Multivariate regression was used to identify fa

SUBMITTER: Tu FF 

PROVIDER: S-EPMC5571860 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature