Kidney stones may increase the risk of coronary heart disease and stroke: A PRISMA-Compliant meta-analysis.

ABSTRACT:

Background

We aimed to quantitatively assess the potential relationship between kidney stones and coronary heart disease or stroke.

Methods

A meta-analysis was conducted on eligibly studies published before 31 May 2016 in PubMed or Embase. The data were pooled, and the relationship was assessed by the random-effect model with inverse variance-weighted procedure. The results were expressed as relative risk (RR) with 95% confidence intervals (95%CI).

Results

Eight studies of 11 cohorts (n = 11) were included in our analysis with 3,658,360 participants and 157,037 cases. We found that a history of kidney stones was associated with increased risk of coronary heart disease (CHD) (RR = 1.24; 95%CI: 1.14-1.36; I = 79.0%, n = 11); similar effect on myocardial infarction, a se

SUBMITTER: Peng JP 

PROVIDER: S-EPMC5572031 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature