Nitrous oxide versus oral sedation for pain management of first-trimester surgical abortion - a randomized study.

ABSTRACT:

Objective

The objective of the study was to compare nitrous oxide with oxygen (N₂O/O₂) to oral hydrocodone/acetaminophen and lorazepam for analgesia during first-trimester surgical abortion.

Study design

This double-blind randomized trial assigned women undergoing first-trimester surgical abortion at<11 weeks' gestation to inhaled N₂O/O₂ vs. oral sedation for pain management. The N₂O/O₂ group received up to 70:30 ratio during the procedure and placebo pills preprocedure; the oral group received inhaled oxygen during the procedure and oral hydrocodone/acetaminophen 5 mg/325 mg and lorazepam 1 mg preprocedure. The primary outcome was maximum procedural pain, assessed on a 100-mm visual analog scale (VAS; anchors

SUBMITTER: Singh RH 

PROVIDER: S-EPMC5572215 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature