Risks of Adverse Events in Advanced CKD: The Chronic Renal Insufficiency Cohort (CRIC) Study.

ABSTRACT:

Background

People with advanced chronic kidney disease are at risk for the development of end-stage renal disease (ESRD), but also many other adverse outcomes, including cardiovascular disease (CVD) events and death. Determination of risk factors that explain the variability in prognosis and timing of these adverse outcomes can aid patient counseling and medical decision making.

Study design

Prospective research cohort.

Setting & participants

1,798 participants with estimated glomerular filtration rates (eGFRs)<30mL/min/1.73m² in the CRIC Study were followed up for a median of 5.5 years.

Predictors

Age, race, sex, eGFR, proteinuria, diabetes mellitus, body mass index, ejection fraction, systolic blood pressure, history of CVD, and smoking history.

SUBMITTER: Grams ME 

PROVIDER: S-EPMC5572665 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature