Linearmycins Activate a Two-Component Signaling System Involved in Bacterial Competition and Biofilm Morphology.

ABSTRACT: Bacteria use two-component signaling systems to adapt and respond to their competitors and changing environments. For instance, competitor bacteria may produce antibiotics and other bioactive metabolites and sequester nutrients. To survive, some species of bacteria escape competition through antibiotic production, biofilm formation, or motility. Specialized metabolite production and biofilm formation are relatively well understood for bacterial species in isolation. How bacteria control these functions when competitors are present is not well studied. To address fundamental questions relating to the competitive mechanisms of different species, we have developed a model system using two species of soil bacteria, Bacillus subtilis and Streptomyces sp. strain Mg1. Using this mod

SUBMITTER: Stubbendieck RM 

PROVIDER: S-EPMC5573067 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature