Cognitive impairment, behavioral impairment, depression, and wish to die in an ALS cohort.

ABSTRACT:

Objective

To evaluate relationships among cognitive, behavioral, and psychiatric/psychosocial measures assessed in a multicenter cohort of patients with amyotrophic lateral sclerosis (ALS).

Methods

Recently diagnosed patients with definite or probable ALS diagnosis were administered 7 standardized psychiatric/psychosocial measures, including the Patient Health Questionnaire for diagnosis of depression and elicitation of wish to die. The Cognitive Behavioral Screen was used to classify both cognitive and behavioral impairment (emotional-interpersonal function). An ALS version of the Frontal Behavioral Inventory and Mini-Mental State Examination were also administered.

Results

Of 247 patients included, 79 patients (32%) had neither cognitive nor behavioral impairment, 1

SUBMITTER: Rabkin J 

PROVIDER: S-EPMC5573192 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature