Cross-Calibrated Dual-Energy X-Ray Absorptiometry Scanners Demonstrate Systematic Bias in Pediatric and Young Adult Females.

ABSTRACT: Consistency of dual-energy X-ray absorptiometry (DXA) scan results is critical for data integrity. For pediatric subjects, the extent to which cross-calibration of DXA scanners alleviates model-to-model scanner differences is unclear. In the current study, DXA bone outcomes were compared for same-day measurements performed using different scanners, cross-calibrated to alleviate discrepancies (Hologic; Discovery A [DISCO] and QDR 4500W [QDR]). Interscanner differences were evaluated in approximately 130 females aged 8-24 yr. Scans were performed in a single session on both QDR and DISCO scanners to compare projected area, bone mineral content, and areal bone mineral density (BMD) outputs for the whole body (total, subhead, head, arm, and leg), forearm (1/3 and ultradistal radius), lumbar sp

SUBMITTER: Dowthwaite JN 

PROVIDER: S-EPMC5573641 | biostudies-literature | 2018 Apr - Jun

REPOSITORIES: biostudies-literature