Dietary trace element intake and liver cancer risk: Results from two population-based cohorts in China.

ABSTRACT: Dietary factors have been hypothesized to affect the risk of liver cancer via various mechanisms, but the influence has been not well studied and the evidence is conflicting. We investigated associations of dietary trace element intake, assessed through a validated food frequency questionnaire, with risk of liver cancer in two prospective cohort studies of 132,765 women (1997-2013) and men (2002-2013) in Shanghai, China. The associations were first evaluated in cohort studies and further assessed in a case-control study nested within these cohorts adjusting for hepatitis B virus infection. For cohort analyses, Cox proportional hazard models were used to estimate hazard ratios and 95% confidence intervals. For nested case-control analyses, conditional logistic regression was used to calcula

SUBMITTER: Ma X 

PROVIDER: S-EPMC5573684 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature