Gabapentin misuse, abuse and diversion: a systematic review.

ABSTRACT:

Background and aims

Since its market release, gabapentin has been presumed to have no abuse potential and subsequently has been prescribed widely off-label, despite increasing reports of gabapentin misuse. This review estimates and describes the prevalence and effects of, motivations behind and risk factors for gabapentin misuse, abuse and diversion.

Methods

Databases were searched for peer-reviewed papers demonstrating gabapentin misuse, characterized by taking a larger dosage than prescribed or taking gabapentin without a prescription, and diversion. All types of studies were considered; grey literature was excluded. Thirty-three papers met inclusion criteria, consisting of 23 case studies and 11 epidemiological reports. Published reports came from the United States, the U

SUBMITTER: Smith RV 

PROVIDER: S-EPMC5573873 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature