Filling in the gaps with non-standard body fluids.

ABSTRACT:

Objectives

Body fluid specimens other than serum, plasma or urine are generally not validated by manufacturers, but analysis of these non-standard fluids can be important for clinical diagnosis and management. Laboratories, therefore, rely on the published literature to better understand the validation and implementation of such tests. This study utilized a data-driven approach to determine the clinical reportable range for 11 analytes, evaluated a total bilirubin assay, and assessed interferences from hemolysis, icterus, and lipemia in non-standard fluids.

Design and methods

Historical measurements in non-standard body fluids run on a Beckman Coulter DxC800 were used to optimize population-specific clinical reportable ranges for albumin, amylase, creatinine, glucose, lactat

SUBMITTER: Lo SY 

PROVIDER: S-EPMC5574517 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature