BMI increase through puberty and adolescence is associated with risk of adult stroke.

ABSTRACT:

Objective

To evaluate the contribution of prepubertal childhood body mass index (BMI) and BMI change through puberty and adolescence, 2 distinct developmental BMI parameters, for risk of adult stroke in men.

Methods

In this population-based study in Gothenburg, Sweden, men born in 1945-1961 with information on both childhood BMI at age 8 and BMI change through puberty and adolescence (BMI at age 20-BMI at age 8) were followed until December 2013 (n = 37,669). Information on stroke events was retrieved from high-quality national registers (918 first stroke events, 672 ischemic stroke events [IS], 207 intracerebral hemorrhage events [ICH]).

Results

BMI increase through puberty and adolescence (hazard ratio [HR] 1.21 per SD increase; 95% confidence interval [CI] 1.14-1.2

SUBMITTER: Ohlsson C 

PROVIDER: S-EPMC5574671 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature