Orientation anisotropy of quantitative MRI relaxation parameters in ordered tissue.

ABSTRACT: In highly organized tissues, such as cartilage, tendons and white matter, several quantitative MRI parameters exhibit dependence on the orientation of the tissue constituents with respect to the main imaging magnetic field (B₀). In this study, we investigated the dependence of multiple relaxation parameters on the orientation of articular cartilage specimens in the B₀. Bovine patellar cartilage-bone samples (n = 4) were investigated ex vivo at 9.4 Tesla at seven different orientations, and the MRI results were compared with polarized light microscopy findings on specimen structure. Dependences of T₂ and continuous wave (CW)-T_1ρ relaxation times on cartilage orientation were confirmed. T₂ (and T₂*) had the highest sensitivity

SUBMITTER: Hanninen N 

PROVIDER: S-EPMC5574987 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature