Modelling of growth kinetics of Vibrio cholerae in presence of gold nanoparticles: effect of size and morphology.

ABSTRACT: Emergence of multiple drug resistant strains of pathogenic bacteria calls for new initiatives to combat infectious diseases. Gold nanoparticles (AuNPs), because of their non-toxic nature and size/shape dependent optical properties, offer interesting possibility. Here we report the antibacterial efficacy of AuNPs of different size and shape (AuNS10, AuNS100 and AuNR10; the number indicating the diameter in nm; S stands for sphere and R for rod) against the classical (O395) and El Tor (N16961) biotypes of Vibrio cholerae, the etiological agent responsible for cholera. Growth kinetics was monitored by measuring optical density at different time intervals and fitted by non-linear regression of modified Buchanan model. Sigmoidal growth curve for VcO395 indicated the existence of single phenotyp

SUBMITTER: Chatterjee T 

PROVIDER: S-EPMC5575114 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature