Effectiveness of an Adjuvant Chemotherapy Regimen for Early-Stage Breast Cancer: A Systematic Review and Network Meta-analysis.

ABSTRACT:

Importance

Different adjuvant chemotherapy regimens are available for early-stage breast cancer. Because conventional meta-analysis does not allow comparing all regimens, we performed a network meta-analysis to identify the most effective adjuvant chemotherapy regimen.

Objective

To find the most effective adjuvant therapy regimen for early-stage breast cancer.

Data sources

We searched MEDLINE, Embase, and the Cochrane Library for articles published before June 2015; the American Society of Clinical Oncology annual meeting abstracts from January 1983 through December 2014; and the American Association for Cancer Research annual meeting abstracts from January 1916 through December 2014. Additionally, we manually searched bibliographies for related references.

Study s

SUBMITTER: Fujii T 

PROVIDER: S-EPMC5575939 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature