Diurnal cortisol rhythms, fatigue and psychosocial factors in five-year survivors of ovarian cancer.

ABSTRACT: Fatigue is a challenge in ovarian cancer survivorship and greatly impacts quality of life. In other cancer populations, fatigue has been associated with abnormal diurnal cortisol patterns. However, little is known about biological and behavioral factors in 5+-year ovarian cancer survivors and potential mechanisms underlying persistent fatigue have not been investigated in this population. Moreover, relationships between neuroendocrine and psychosocial factors in 5+-year ovarian cancer survivors have not been studied. We addressed these issues by examining relationships between diurnal cortisol rhythms, fatigue, life stress, and social support in 30 survivors of ovarian cancer who were assessed at least 5 years (mean=6.20years) following their primary diagnosis. Flatter diurnal cortisol slo

SUBMITTER: Cuneo MG 

PROVIDER: S-EPMC5575993 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature