Colonization with 19F and other pneumococcal conjugate vaccine serotypes in children in St. Louis, Missouri, USA.

ABSTRACT:

Background

The epidemiology of nasopharyngeal (NP) pneumococcal carriage varies with geography and has changed in response to pneumococcal conjugate vaccine (PCV): a low prevalence (3% or less of colonizing isolates) of colonization by vaccine-type (VT) pneumococcal serotypes after PCV introduction has been reported. The primary goal of this study was to determine the VT serotype prevalence of NP pneumococcal colonization of children residing in the St. Louis, MO, USA metropolitan area following introduction of the 13-valent PCV in 2010. The secondary goal of this study was to identify characteristics associated with NP pneumococcal carriage of any serotype.

Methods

Between July 2013 and April 2016, we enrolled 397 healthy children, aged 0-17years, who required sedation for

SUBMITTER: McFarland M 

PROVIDER: S-EPMC5576556 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature