Schizophrenia genetics in the genome-wide era: a review of Japanese studies.

ABSTRACT: The introduction of the genome-wide association study transformed schizophrenia genetics research and has promoted a genome-wide mindset that has stimulated the development of genomic technology, enabling departures from the traditional candidate gene approach. As result, we have witnessed a decade of major discoveries in schizophrenia genetics and the development of genome-wide approaches to the study of copy number variants. These genomic technologies have primarily been applied in populations of European descent. However, more recently both genome-wide association study and copy number variant studies in Asian populations have begun to emerge. In this invited review, we provide concise summaries of the schizophrenia genome-wide association study and copy number variant literature with s

SUBMITTER: Kanazawa T 

PROVIDER: S-EPMC5577232 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature