Chicken domestication changes expression of stress-related genes in brain, pituitary and adrenals.

ABSTRACT: Domesticated species have an attenuated behavioral and physiological stress response compared to their wild counterparts, but the genetic mechanisms underlying this change are not fully understood. We investigated gene expression of a panel of stress response-related genes in five tissues known for their involvement in the stress response: hippocampus, hypothalamus, pituitary, adrenal glands and liver of domesticated White Leghorn chickens and compared it with the wild ancestor of all domesticated breeds, the Red Junglefowl. Gene expression was measured both at baseline and after 45 min of restraint stress. Most of the changes in gene expression related to stress were similar to mammals, with an upregulation of genes such as FKBP5, C-FOS and EGR1 in hippocampus and hyp

SUBMITTER: Lotvedt P 

PROVIDER: S-EPMC5577413 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature