The organisational value of diagnostic strategies using high-sensitivity troponin for patients with possible acute coronary syndromes: a trial-based cost-effectiveness analysis.

ABSTRACT:

Objectives

To evaluate hospital-specific health economic implications of different protocols using high-sensitivity troponin I for the assessment of patients with chest pain.

Design

A cost prediction model and an economic microsimulation were developed using a cohort from a single centre recruited as part of the (ADAPT) trial, a prospective observational trial conducted from 2008 to 2011. The model was populated with 40 000 bootstrapped samples in five high-sensitivity troponin I-enabled algorithms versus standard care.

Setting

Adult emergency department (ED) of a tertiary referral hospital.

Participants

Data were available for 938 patients who presented to the ED with at least 5 min of symptoms suggestive of acute coronary syndrome. The analyses included 719 p

SUBMITTER: Julicher P 

PROVIDER: S-EPMC5577894 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature