Whole-loop mitochondrial DNA D-loop sequence variability in Egyptian Arabian equine matrilines.

ABSTRACT:

Background

Egyptian Arabian horses have been maintained in a state of genetic isolation for over a hundred years. There is only limited genetic proof that the studbook records of female lines of Egyptian Arabian pedigrees are reliable. This study characterized the mitochondrial DNA (mtDNA) signatures of 126 horses representing 14 matrilines in the Egyptian Agricultural Organization (EAO) horse-breeding program.

Findings

Analysis of the whole D-loop sequence yielded additional information compared to hypervariable region-1 (HVR1) analysis alone, with 42 polymorphic sites representing ten haplotypes compared to 16 polymorphic sites representing nine haplotypes, respectively. Most EAO haplotypes belonged to ancient haplogroups, suggesting origin from a wide geographical area ov

SUBMITTER: Hudson W 

PROVIDER: S-EPMC5578668 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature