Annulus fibrosus functional extrafibrillar and fibrous mechanical behaviour: experimental and computational characterisation.

ABSTRACT: The development of current surgical treatments for intervertebral disc damage could benefit from virtual environment accounting for population variations. For such models to be reliable, a relevant description of the mechanical properties of the different tissues and their role in the functional mechanics of the disc is of major importance. The aims of this work were first to assess the physiological hoop strain in the annulus fibrosus in fresh conditions (n = 5) in order to extract a functional behaviour of the extrafibrillar matrix; then to reverse-engineer the annulus fibrosus fibrillar behaviour (n = 6). This was achieved by performing both direct and global controlled calibration of material parameters, accounting for the whole process of experimental design and in si

SUBMITTER: Mengoni M 

PROVIDER: S-EPMC5579130 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature