Comparison of effects of intravenous midazolam and ketamine on emergence agitation in children: Randomized controlled trial.

ABSTRACT:

Objective

A prospective, double-blind, randomized controlled trial to compare the effect of preoperative midazolam or ketamine on the incidence of emergence agitation (EA) following sevoflurane anaesthesia in children.

Methods

Paediatric patients (2-6 years old) undergoing ophthalmic surgery were allocated to receive premedication with either 0.1 mg/kg midazolam or 1 mg/kg ketamine. Incidence of EA and postoperative pain scores were recorded at 10-min intervals in the postanaesthetic care unit (PACU). The use of EA rescue medications (fentanyl or midazolam) was recorded.

Results

The incidence of EA was significantly lower in the ketamine group (n = 33) than the midazolam group (n = 34) at 10 and 20 min after transfer to PACU. There was no significant difference in ove

SUBMITTER: Kim KM 

PROVIDER: S-EPMC5580063 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature