Decision aids for second-line palliative chemotherapy: a randomised phase II multicentre trial.

ABSTRACT:

Background

There is increasing recognition of the delicate balance between the modest benefits of palliative chemotherapy and the burden of treatment. Decision aids (DAs) can potentially help patients with advanced cancer with these difficult treatment decisions, but providing detailed information could have an adverse impact on patients' well-being. The objective of this randomised phase II study was to evaluate the safety and efficacy of DAs for patients with advanced cancer considering second-line chemotherapy.

Methods

Patients with advanced breast or colorectal cancer considering second-line treatment were randomly assigned to usual care (control group) or usual care plus a DA (intervention group) in a 1:2 ratio. A nurse offered a DA with information on adverse events, t

SUBMITTER: Oostendorp LJM 

PROVIDER: S-EPMC5580234 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature