Increasing use of allogeneic hematopoietic cell transplantation in patients aged 70 years and older in the United States.

ABSTRACT: In this study, we evaluated trends and outcomes of allogeneic hematopoietic cell transplantation (HCT) in adults ≥70 years with hematologic malignancies across the United States. Adults ≥70 years with a hematologic malignancy undergoing first allogeneic HCT in the United States between 2000 and 2013 and reported to the Center for International Blood and Marrow Transplant Research were eligible. Transplant utilization and transplant outcomes, including overall survival (OS), progression-free survival (PFS), and transplant-related mortality (TRM) were studied. One thousand one hundred and six patients ≥70 years underwent HCT across 103 transplant centers. The number and proportion of allografts performed in this population rose markedly over the past decade, accounting for 0.1% of transplant

SUBMITTER: Muffly L 

PROVIDER: S-EPMC5580273 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature