Ontology highlight
ABSTRACT:
SUBMITTER: Liu S
PROVIDER: S-EPMC5580719 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Genome research 20170707 9
Long noncoding RNAs (lncRNAs) mediate important epigenetic regulation in a wide range of biological processes and diseases. We applied comprehensive analyses of RNA-seq and CAGE-seq (cap analysis of gene expression and sequencing) to characterize the dynamic changes in lncRNA expression in rhesus macaque (<i>Macaca mulatta</i>) brain in four representative age groups. We identified 18 anatomically diverse lncRNA modules and 14 mRNA modules representing spatial, age, and sex specificities. Spatio ...[more]