Human orbital and anterior medial prefrontal cortex: Intrinsic connectivity parcellation and functional organization.

ABSTRACT: The orbital and medial prefrontal cortex (OMPFC) has been implicated in decision-making, reward and emotion processing, and psychopathology, such as depression and obsessive-compulsive disorder. Human and monkey anatomical studies indicate the presence of various cortical subdivisions and suggest that these are organized in two extended networks, a medial and an orbital one. Attempts have been made to replicate these neuroanatomical findings in vivo using MRI techniques for imaging connectivity. These revealed several consistencies, but also many inconsistencies between reported results. Here, we use fMRI resting-state functional connectivity (FC) and data-driven modularity optimization to parcellate the OMPFC to investigate replicability of in vivo parcellation more systematically. By col

SUBMITTER: Samara Z 

PROVIDER: S-EPMC5581738 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature