Finding the right route for insulin delivery - an overview of implantable pump therapy.

ABSTRACT:

Introduction

Implantable pump therapy adopting the intraperitoneal route of insulin delivery has been available for the past three decades. The key rationale for implantable pump therapy is the restoration of the portal-peripheral insulin gradient of the normal physiology. Uptake in clinical practice is limited to specialized centers and selected patient populations. Areas covered: Implantable pump therapy is discussed, including technical aspects, rationale for its use, and glycemic and non-glycemic effects. Target populations, summaries of clinical studies and issues related to implantable pump therapy are highlighted. Limitations of implantable pump therapy and its future outlook in clinical practice are presented. Expert opinion: Although intraperitoneal insulin delivery appear

SUBMITTER: Bally L 

PROVIDER: S-EPMC5581917 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature