Sex disparities in substance abuse research: Evaluating 23 years of structural neuroimaging studies.

ABSTRACT:

Background

Sex differences in brain structure and clinical course of substance use disorders underscores the need to include women in structural brain imaging studies. The NIH has supported the need for research to address sex differences. We evaluated female enrollment in substance abuse structural brain imaging research and the methods used to study sex differences in substance effects.

Methods

Structural brain imaging studies published through 2016 (n=230) were evaluated for number of participants by sex and substance use status and methods used to evaluate sex differences. Temporal trends in the numbers of participants by sex and substance use status were analyzed. We evaluated how often sex effects were appropriately analyzed and the proportion of studies that found sex

SUBMITTER: Lind KE 

PROVIDER: S-EPMC5581940 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature