Molecular analysis of alternative transcripts of equine AXL receptor tyrosine kinase gene.

ABSTRACT:

Objective

Since athletic performance is a most importance trait in horses, most research focused on physiological and physical studies of horse athletic abilities. In contrast, the molecular analysis as well as the regulatory pathway studies remain insufficient for evaluation and prediction of horse athletic abilities. In our previous study, we identified AXL receptor tyrosine kinase (AXL) gene which was expressed as alternative spliced isoforms in skeletal muscle during exercise. In the present study, we validated two AXL alternative splicing transcripts (named as AXLa for long form and AXLb for short form) in equine skeletal muscle to gain insight(s) into the role of each alternative transcript during exercise.

Methods

We validated two is

SUBMITTER: Park JW 

PROVIDER: S-EPMC5582333 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature