Occupational exposure to respirable crystalline silica and chronic non-malignant renal disease: systematic review and meta-analysis.

ABSTRACT:

Background

While occupational exposure to respirable silica is known to lead to lung disease, most notably silicosis, its association with chronic kidney disease is unclear.

Objectives

This review explores the association between occupational exposure to respirable silica and chronic non-malignant renal disease such as glomerulonephritis. The evidence has been collected and compiled. Possible sources of bias are thoroughly discussed.

Methods

Cohort studies with silica exposure and case-control studies of renal disease were searched in PubMed until January 2015. Two authors independently abstracted data; any disagreement was resolved by consulting a third reviewer. A meta-analysis was performed to evaluate the association to silica exposure.

Results

A total of 2

SUBMITTER: Mohner M 

PROVIDER: S-EPMC5583269 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature