Childhood height increases the risk of prostate cancer mortality.

ABSTRACT:

Background

Adult body size is positively associated with aggressive and fatal prostate cancers. It is unknown whether these associations originate in early life. Therefore, we investigated if childhood height, body mass index (BMI; kg/m(2)) and growth are associated with prostate cancer-specific mortality and survival.

Methods

Subjects were 125,208 men from the Copenhagen School Health Records Register, born 1930-1969 with height and weight measurements at ages 7-13years. Linkage to the Danish Cancer Registry and the Register of Causes of Death enabled identification of incident and fatal prostate cancers. Cox proportional hazards regressions were performed.

Results

630 men had prostate cancer recorded as the underlying cause of death. Childhood height at age 13years

SUBMITTER: Aarestrup J 

PROVIDER: S-EPMC5584054 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature