A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer.

ABSTRACT:

Background

Routine resection of cavity shave margins (additional tissue circumferentially around the cavity left by partial mastectomy) may reduce the rates of positive margins (margins positive for tumor) and reexcision among patients undergoing partial mastectomy for breast cancer.

Methods

In this randomized, controlled trial, we assigned, in a 1:1 ratio, 235 patients with breast cancer of stage 0 to III who were undergoing partial mastectomy, with or without resection of selective margins, to have further cavity shave margins resected (shave group) or not to have further cavity shave margins resected (no-shave group). Randomization occurred intraoperatively after surgeons had completed standard partial mastectomy. Positive margins were defined as tumor touching the edge o

SUBMITTER: Chagpar AB 

PROVIDER: S-EPMC5584380 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature